Additional file 10: of Combination therapy with c-met inhibitor and TRAIL enhances apoptosis in dedifferentiated liposarcoma patient-derived cells

Figure S8. Effect of apoptosis by combination treatment with PF and/ or rhTRAIL and combined with DR5 siRNA. To determine the direct roles of DR5 in PF-induced TRAIL sensitization, LPS224 cells were treated with DR5 siRNA, followed by co-treatment with PF (5 μM) and rhTRAIL (5 ng/ml) for 48 h. Representative Western blots of caspase-3, caspase-7 (a), and caspase-8 (b) were shown. (PPTX 275 kb)