10.6084/m9.figshare.9895055.v1 Desirée Perlee Desirée Perlee Alex Vos Alex Vos Brendon Scicluna Brendon Scicluna Anja Maag Anja Maag Pablo Mancheño Pablo Mancheño Olga Rosa Olga Rosa Wilfried Dalemans Wilfried Dalemans Sandrine Florquin Sandrine Florquin Cornelis Veer Cornelis Veer Eleuterio Lombardo Eleuterio Lombardo Tom Poll Tom Poll Additional file 1: of Role of tissue factor in the procoagulant and antibacterial effects of human adipose-derived mesenchymal stem cells during pneumosepsis in mice Springer Nature 2019 Sepsis Mesenchymal stem cells Immunomodulation Coagulation 2019-09-24 03:39:13 Figure https://springernature.figshare.com/articles/figure/Additional_file_1_of_Role_of_tissue_factor_in_the_procoagulant_and_antibacterial_effects_of_human_adipose-derived_mesenchymal_stem_cells_during_pneumosepsis_in_mice/9895055 Figure S1. ASCs infusion results in an increased inflammatory response in the lungs in uninfected and infected mice. Mice were treated with 1 × 106 cryopreserved ASCs intravenously and lungs were harvested 3 hours thereafter. Some mice were infected with K. pneumoniae via the airways one hour prior to ASC infusion. ASCs were preincubated with a blocking anti-tissue factor antibody or isotype control prior to infusion. (A) Representative photographs of H&E-stained tissue sections of infected and uninfected lungs at 4 hours; original magnification 10x. (B) The extent of inflammation scored on H&E tissue sections as total HE score. Data are expressed as bars for panel B (mean with SD). N = 4 mice per group. * p < 0.05 versus the control group. (TIF 3283 kb)