10.6084/m9.figshare.9751100.v1
Yan Zhu
Yan
Zhu
Jingjing Xie
Jingjing
Xie
Hong Sun
Hong
Sun
Additional file 1: of Three miRNAs cooperate with host genes involved in human cardiovascular disease
Springer Nature
2019
PhyloP score
host gene CDH 13
miR -6863 gene
Table S 3.
30 mammals
Table S 2.
Validated targets
Table S 1.
Evolutionary conservation
Figure S 4. Genomic location
sequence conservation
Figure S 3. Genomic location
host gene SLC 12A
disease Figure S 1. Schematic representation
miR -5582 gene
Figure S 2. Genomic location
DOC 6113 kb
host gene CKAP 5
GSEA analysis
miR -3182 gene
NetWAS scores
2019-08-30 04:38:28
Journal contribution
https://springernature.figshare.com/articles/journal_contribution/Additional_file_1_of_Three_miRNAs_cooperate_with_host_genes_involved_in_human_cardiovascular_disease/9751100
Figure S1. Schematic representation of the study design. Figure S2. Genomic location and sequence conservation of the human miR-3182 gene. A, Evolutionary conservation across 30 mammals is measured by PhastCons and PhyloP score. B, Pairwise alignment between the human miR-3182 gene and its gorila ortholog. Figure S3. Genomic location and sequence conservation of the human miR-6863 gene. Evolutionary conservation across 30 mammals is measured by PhastCons and PhyloP score. Figure S4. Genomic location and sequence conservation of the human miR-5582 gene. Evolutionary conservation across 30 mammals is measured by PhastCons and PhyloP score. Table S1. Targets of miR-3182 used for GSEA analysis. The NetWAS scores, which describe the probability of interaction between the host gene CDH13 and the predicted targets of miR-3182, are replaced by their fractional ranks. Validated targets are highlighted with a star. Table S2. Targets of miR-6863 used for GSEA analysis. The NetWAS scores, which describe the probability of interaction between the host gene SLC12A3 and the predicted targets of miR-5582, are replaced by their fractional ranks. Validated targets are highlighted with a star. Table S3. Targets of miR-5582 used for GSEA analysis. The NetWAS scores, which describe the probability of interaction between the host gene CKAP5 and the predicted targets gene of miR-5582, are replaced by their fractional ranks. Validated targets are highlighted with a star. (DOC 6113 kb)