10.6084/m9.figshare.9751100.v1 Yan Zhu Yan Zhu Jingjing Xie Jingjing Xie Hong Sun Hong Sun Additional file 1: of Three miRNAs cooperate with host genes involved in human cardiovascular disease Springer Nature 2019 PhyloP score host gene CDH 13 miR -6863 gene Table S 3. 30 mammals Table S 2. Validated targets Table S 1. Evolutionary conservation Figure S 4. Genomic location sequence conservation Figure S 3. Genomic location host gene SLC 12A disease Figure S 1. Schematic representation miR -5582 gene Figure S 2. Genomic location DOC 6113 kb host gene CKAP 5 GSEA analysis miR -3182 gene NetWAS scores 2019-08-30 04:38:28 Journal contribution https://springernature.figshare.com/articles/journal_contribution/Additional_file_1_of_Three_miRNAs_cooperate_with_host_genes_involved_in_human_cardiovascular_disease/9751100 Figure S1. Schematic representation of the study design. Figure S2. Genomic location and sequence conservation of the human miR-3182 gene. A, Evolutionary conservation across 30 mammals is measured by PhastCons and PhyloP score. B, Pairwise alignment between the human miR-3182 gene and its gorila ortholog. Figure S3. Genomic location and sequence conservation of the human miR-6863 gene. Evolutionary conservation across 30 mammals is measured by PhastCons and PhyloP score. Figure S4. Genomic location and sequence conservation of the human miR-5582 gene. Evolutionary conservation across 30 mammals is measured by PhastCons and PhyloP score. Table S1. Targets of miR-3182 used for GSEA analysis. The NetWAS scores, which describe the probability of interaction between the host gene CDH13 and the predicted targets of miR-3182, are replaced by their fractional ranks. Validated targets are highlighted with a star. Table S2. Targets of miR-6863 used for GSEA analysis. The NetWAS scores, which describe the probability of interaction between the host gene SLC12A3 and the predicted targets of miR-5582, are replaced by their fractional ranks. Validated targets are highlighted with a star. Table S3. Targets of miR-5582 used for GSEA analysis. The NetWAS scores, which describe the probability of interaction between the host gene CKAP5 and the predicted targets gene of miR-5582, are replaced by their fractional ranks. Validated targets are highlighted with a star. (DOC 6113 kb)