Longhini, Federico Maugeri, Jessica Andreoni, Cristina Ronco, Chiara Bruni, Andrea Garofalo, Eugenio Pelaia, Corrado Cavicchi, Camilla Pintaudi, Sergio Navalesi, Paolo MOESM1 of Electrical impedance tomography during spontaneous breathing trials and after extubation in critically ill patients at high risk for extubation failure: a multicenter observational study Additional file 1: Table S1. Criteria considered in the study protocol. Criteria for increased risk for post-extubation respiratory failure, SBT eligibility, SBT failure, post-extubation respiratory failure and reintubation are presented from left to right. Table S2. Receiving Operating Curves of ∆Vt%, ∆EELI, inhomogeneity index, RR/Vt and PaO2/FiO2 for SBT failure prediction. The Youden index, area under the curve (AUC), sensibility, specificity, positive (LR +) and negative (LR −) likelihood ratios are presented for EIT data, RR/Vt and PaO2/FiO2 for SBT failure prediction. Table S3. ABGs and RR/Vt in patients with extubation success and failure. Data are separately presented for patients succeeding and failing extubation. Table S4. Receiving Operating Curves of ∆Vt%, ∆EELI, inhomogeneity index, RR/Vt and PaO2/FiO2 for extubation failure prediction. The Youden index, area under the curve (AUC), sensibility, specificity, positive (LR +) and negative (LR −) likelihood ratios are presented for EIT data, RR/Vt and PaO2/FiO2 for extubation failure prediction. Table S5. EIT data in patients with “rescue” NIV success and failure. EIT parameters are separately presented for patients succeeding and failing rescue CPAP/NIV. Table S6. EIT data in patients with respiratory and non-respiratory reasons of extubation failure. EIT parameters are separately presented for patients with extubation failure secondary to respiratory and non-respiratory causes. Figure S1. Flow diagram of screened and enrolled patients. The flow of patients screened for the study (n = 1555), assessed for eligibility (n = 145), excluded (with the reason of exclusion) (n = 65), enrolled in the study (n = 80), and analyzed (n = 78) is shown. Mechanical ventilation;Weaning;Spontaneous breathing trial;Post-extubation respiratory failure;Extubation failure;Electrical impedance tomography 2019-08-14
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