%0 Figure %A Du, Changchun %A Bevers, Jack %A Cook, Ryan %A Lombana, T. %A Rajasekaran, Kamalakannan %A Matsumoto, Marissa %A Spiess, Christoph %A Kim, Jeong %A Ye, Zhengmao %D 2019 %T Additional file 6: of MICA immune complex formed with alpha 3 domain-specific antibody activates human NK cells in a Fc-dependent manner %U https://springernature.figshare.com/articles/figure/Additional_file_6_of_MICA_immune_complex_formed_with_alpha_3_domain-specific_antibody_activates_human_NK_cells_in_a_Fc-dependent_manner/9277703 %R 10.6084/m9.figshare.9277703.v1 %2 https://springernature.figshare.com/ndownloader/files/16881140 %K MICA %K NKG2D %K Immune suppression %K Anti-MICA %K Immunotherapy %X Figure S6. MICA antibodies induce ADCC. C1R-MICA*002 cell line ADCC experiment was conducted by co-culturing C1R-MICA*002 cell line with primary NK cells (10 to 1 effector to target ratio) in the presence of 10 μg/mL control hIgG1 or anti-MICA antibodies, 6E1, 5E10 or 7G10 for 4 h, the data is the average of 3 technical replicates with error bar representing SD, and the dataset is a representative of 3 independent experiments with p-values generated from unpaired t-test. *p > = 0.05; **p < 0.05. (JPG 95 kb) %I figshare