10.6084/m9.figshare.9162956.v1
Jérôme Caron
Jérôme
Caron
Véronique Pène
Véronique
Pène
Laia Tolosa
Laia
Tolosa
Maxime Villaret
Maxime
Villaret
Eléanor Luce
Eléanor
Luce
Angélique Fourrier
Angélique
Fourrier
Jean-Marie Heslan
Jean-Marie
Heslan
Samir Saheb
Samir
Saheb
Eric Bruckert
Eric
Bruckert
María Gómez-Lechón
María
Gómez-Lechón
Tuan Nguyen
Tuan
Nguyen
Arielle Rosenberg
Arielle
Rosenberg
Anne Weber
Anne
Weber
Anne Dubart-Kupperschmitt
Anne
Dubart-Kupperschmitt
Additional file 2: of Low-density lipoprotein receptor-deficient hepatocytes differentiated from induced pluripotent stem cells allow familial hypercholesterolemia modeling, CRISPR/Cas-mediated genetic correction, and productive hepatitis C virus infection
Springer Nature
2019
Cardiovascular disease
Genome editing
Cell models
Cell therapy
Gene therapy
Personalized medicine
2019-07-30 04:18:22
Figure
https://springernature.figshare.com/articles/figure/Additional_file_2_of_Low-density_lipoprotein_receptor-deficient_hepatocytes_differentiated_from_induced_pluripotent_stem_cells_allow_familial_hypercholesterolemia_modeling_CRISPR_Cas-mediated_genetic_correction_and_productive_hepatitis_C_vi/9162956
Figure S2. Confirmation of the correct homologous recombination during the insertion of the therapeutic cassette. (A-B) Forward (A) and reverse (B) sequence alignments for the 5′ homology arm between corr-FH-iPSC (lower lane) and the plasmid used for the homologous recombination (upper lane). (C-D) Forward (C) and reverse (D) sequence alignments for the 3′ homology arm between corr-FH-iPSC (lower lane) and the plasmid used for the homologous recombination (upper lane) . (TIF 3705 kb)