10.6084/m9.figshare.9162956.v1 Jérôme Caron Jérôme Caron Véronique Pène Véronique Pène Laia Tolosa Laia Tolosa Maxime Villaret Maxime Villaret Eléanor Luce Eléanor Luce Angélique Fourrier Angélique Fourrier Jean-Marie Heslan Jean-Marie Heslan Samir Saheb Samir Saheb Eric Bruckert Eric Bruckert María Gómez-Lechón María Gómez-Lechón Tuan Nguyen Tuan Nguyen Arielle Rosenberg Arielle Rosenberg Anne Weber Anne Weber Anne Dubart-Kupperschmitt Anne Dubart-Kupperschmitt Additional file 2: of Low-density lipoprotein receptor-deficient hepatocytes differentiated from induced pluripotent stem cells allow familial hypercholesterolemia modeling, CRISPR/Cas-mediated genetic correction, and productive hepatitis C virus infection Springer Nature 2019 Cardiovascular disease Genome editing Cell models Cell therapy Gene therapy Personalized medicine 2019-07-30 04:18:22 Figure https://springernature.figshare.com/articles/figure/Additional_file_2_of_Low-density_lipoprotein_receptor-deficient_hepatocytes_differentiated_from_induced_pluripotent_stem_cells_allow_familial_hypercholesterolemia_modeling_CRISPR_Cas-mediated_genetic_correction_and_productive_hepatitis_C_vi/9162956 Figure S2. Confirmation of the correct homologous recombination during the insertion of the therapeutic cassette. (A-B) Forward (A) and reverse (B) sequence alignments for the 5′ homology arm between corr-FH-iPSC (lower lane) and the plasmid used for the homologous recombination (upper lane). (C-D) Forward (C) and reverse (D) sequence alignments for the 3′ homology arm between corr-FH-iPSC (lower lane) and the plasmid used for the homologous recombination (upper lane) . (TIF 3705 kb)