Additional file 3: of PYK2 promotes HER2-positive breast cancer invasion Shaymaa IK. Al-Juboori Jayakumar Vadakekolathu Sarra Idri Sarah Wagner Dimitrios Zafeiris Joshua RD. Pearson Rukaia Almshayakhchi Michele Caraglia Vincenzo Desiderio Amanda Miles David Boocock Graham Ball Tarik Regad 10.6084/m9.figshare.8172080.v1 https://springernature.figshare.com/articles/figure/Additional_file_3_of_PYK2_promotes_HER2-positive_breast_cancer_invasion/8172080 Figure S3. (A) Heatmap representing the top 25 upregulated and downregulated proteins in untreated control and PYK2 knockdown MDA-MB-453 cells. (B) Heatmap representing the top 25 upregulated and downregulated proteins in untreated control and PYK2 knockdown metformin-treated MDA-MB-453 cells. (JPG 1535 kb) 2019-05-22 05:00:00 Pure HER2 breast Cancer Metformin PYK2/PTK2B Chemoresistance Breast cancer stem cells