10.6084/m9.figshare.7802927.v1 Lufeng Zheng Lufeng Zheng Qianqian Guo Qianqian Guo Chenxi Xiang Chenxi Xiang Shijia Liu Shijia Liu Yuzhang Jiang Yuzhang Jiang Lanlan Gao Lanlan Gao Haiwei Ni Haiwei Ni Ting Wang Ting Wang Qiong Zhao Qiong Zhao Hai Liu Hai Liu Yingying Xing Yingying Xing Yaohui Wang Yaohui Wang Xiaoman Li Xiaoman Li Tao Xi Tao Xi Additional file 14: of Transcriptional factor six2 promotes the competitive endogenous RNA network between CYP4Z1 and pseudogene CYP4Z2P responsible for maintaining the stemness of breast cancer cells Springer Nature 2019 CYP4Z1 Pseudogene CYP4Z2P ceRNET_CC Six2 Stemness Chemoresistance Breast cancer 2019-03-04 05:00:00 Figure https://springernature.figshare.com/articles/figure/Additional_file_14_of_Transcriptional_factor_six2_promotes_the_competitive_endogenous_RNA_network_between_CYP4Z1_and_pseudogene_CYP4Z2P_responsible_for_maintaining_the_stemness_of_breast_cancer_cells/7802927 Figure S8. Proposed model in which transcriptional factor six2-mediated regulation of ceRNET_CC is responsible for breast CSC formation and thus drug resistance. Transcriptional factor six2 induces the progression of ceRNET_CC by directly binding to the promoters of CYP4Z1 and the pseudogene CYP4Z2P. This six2/ceRNET_CC regulatory axis results in breast CSC progression and thus enhances drug sensitivity. (TIF 242 kb)