Additional file 1: of Cathelicidin-related antimicrobial peptide protects against myocardial ischemia/reperfusion injury
Yihua Bei
Li-Long Pan
Qiulian Zhou
Cuimei Zhao
Yuan Xie
Chengfei Wu
Xiangmin Meng
Huanyu Gu
Jiahong Xu
Lei Zhou
Joost Sluijter
Saumya Das
Birgitta Agerberth
Jia Sun
Junjie Xiao
10.6084/m9.figshare.7744304.v1
https://springernature.figshare.com/articles/journal_contribution/Additional_file_1_of_Cathelicidin-related_antimicrobial_peptide_protects_against_myocardial_ischemia_reperfusion_injury/7744304
Figure S1. Western blot analysis for Akt and ERK1/2 phosphorylation level in neonatal rat cardiomyocytes (NRCMs) treated with Akt or MEK inhibitor. (a) NRCMs were treated with Akt inhibitor MK2206 (10 nM, 24 h) or control under the condition of oxygen glucose deprivation/reperfusion (OGDR) (n = 3). (b) NRCMs were treated with MEK inhibitor PD98059 (50 μM, 24 h) or control under the condition of OGDR (n = 3). All membranes were probed, stripped, and then reprobed for determining the phosphorylation levels of Akt and ERK1/2. Data were expressed as mean ± SD. *, P < 0.05; **, P < 0.01; ***, P < 0.001. (PDF 148 kb)
2019-02-20 05:00:00
Cathelicidin
CRAMP
LL-37
Ischemia/reperfusion injury
Cardiomyocyte
Apoptosis