%0 Journal Article %A Giraud, Emilie %A Rouault, Eline %A Fiette, Laurence %A Colle, Jean-Hervé %A Smirlis, Despoina %A Melanitou, Evie %D 2019 %T Additional file 8: of Osteopontin in the host response to Leishmania amazonensis %U https://springernature.figshare.com/articles/journal_contribution/Additional_file_8_of_Osteopontin_in_the_host_response_to_Leishmania_amazonensis/7699133 %R 10.6084/m9.figshare.7699133.v1 %2 https://springernature.figshare.com/ndownloader/files/14328755 %K Osteopontin %K Macrophage %K Inflammation %K Inflammasome %K Pyroptosis %K Parasites %K Leishmania amazonensis %K C57BL/6 mice %X Figure S6. Evolution of representative ear phenotypic lesions at Day 48 and 104. A. C57BL/6 wild type phenotypic scores at Day 48 p. i.: 8/10 (80%) mild inflammation. At Day 104: 4/10 (40%) moderate to severe inflammation and 6/10 (60%) tissue disrupted at the level of infection. B. C57BL/6−/− mice phenotypic scores at D48: 11/11 (100%) severe inflammatory lesions. At Day104: 7/11 (64%) destructive inflammatory lesions and 4/11 (36%) damaged tissue. (PDF 611 kb) %I figshare