10.6084/m9.figshare.7577057.v1
Louis Allott
Louis
Allott
Cecilia Miranda
Cecilia
Miranda
Angela Hayes
Angela
Hayes
Florence Raynaud
Florence
Raynaud
Christopher Cawthorne
Christopher
Cawthorne
Graham Smith
Graham
Smith
Additional file 1: of Synthesis of a benzoxazinthione derivative of tanaproget and pharmacological evaluation for PET imaging of PR expression
Springer Nature
2019
PET
Fluorine-18
Progesterone
Steroid hormone receptor
Tanaproget
Fluoropyridine metabolism
2019-01-10 05:00:00
Journal contribution
https://springernature.figshare.com/articles/journal_contribution/Additional_file_1_of_Synthesis_of_a_benzoxazinthione_derivative_of_tanaproget_and_pharmacological_evaluation_for_PET_imaging_of_PR_expression/7577057
Reaction Scheme for synthesis of precursor 7; 1H, 13C, 19F NMR data and HPLC purity analysis for compounds 1, 2, 3, 4, 5, 6 and 7; radio-HPLC analysis of [18F]1 and [18F]2; Molar activity calibration curve; Log D calculation raw data; plotted data for T47D assay; In vitro cross reactivity assay data; TACs for in vivo evaulation of [18F]2; ex vivo biodistribution data for [18F]2; HPLC metabolite analysis for [18/19F]2; MS metabolite analysis for [19F]2. (DOCX 3180 kb)