Additional file 2: of A rare population of tumor antigen-specific CD4+CD8+ double-positive ιβ T lymphocytes uniquely provide CD8-independent TCR genes for engineering therapeutic T cells
Junko Matsuzaki
Takemasa Tsuji
Thinle Chodon
Courtney Ryan
Richard Koya
Kunle Odunsi
10.6084/m9.figshare.7569725.v1
https://springernature.figshare.com/articles/journal_contribution/Additional_file_2_of_A_rare_population_of_tumor_antigen-specific_CD4_CD8_double-positive__T_lymphocytes_uniquely_provide_CD8-independent_TCR_genes_for_engineering_therapeutic_T_cells/7569725
Intensity of HLA-A2 and NY-ESO-1 expression on A*02+NY-ESO-1+ cancer cell lines. Surface HLA-A2 (clone: BB7.2) and cytoplasmic NY-ESO-1 (clone: 219â510) expression was analyzed by flow cytometry. Shaded histogram is unstained control. (DOCX 88 kb)
2019-01-09 05:00:00
NY-ESO-1
TCR gene-engineering
CD4+CD8+ double-positive T cells
HLA-A*02:01
Anti-tumor function
Adoptive cell therapy
Ovarian cancer