10.6084/m9.figshare.7459892.v1 Nzali Campbell Nzali Campbell David Weitzenkamp David Weitzenkamp Ian Campbell Ian Campbell Ronald Schmidt Ronald Schmidt Chindo Hicks Chindo Hicks Michael Morgan Michael Morgan David Irwin David Irwin John Tentler John Tentler Additional file 6: of “Omics” data integration and functional analyses link Enoyl-CoA hydratase, short chain 1 to drug refractory dilated cardiomyopathy Springer Nature 2018 drDCM Omics RNA-Seq IPA ECHS1 DBT MIR3944 rs10466126 BCAA Mitochondria 2018-12-12 05:00:00 Presentation https://springernature.figshare.com/articles/presentation/Additional_file_6_of_Omics_data_integration_and_functional_analyses_link_Enoyl-CoA_hydratase_short_chain_1_to_drug_refractory_dilated_cardiomyopathy/7459892 Figure S5. Proposed schematic: Dysfunction in the mitochondria. Legend: Arrows (red) pointing up represent up-regulated genes and arrows (green) pointing down, down-regulated genes. Printed in blue indicates putative modifiers and in red mutations. In bold print indicates genes carrying a variant. Orange arrows indicate the flow of catalysis in the fatty acid beta-oxidation pathway. Green arrows show the flow of catalysis in the Leucine degradation 1 pathway. Purple arrows show the flow of catalysis in the Valine degradation 1 pathway. Blue arrows indicate the flow of catalysis in the Isoleucine degradation 1 pathway. In boxes at the end of each pathway are proposed products of each pathway. (PPTX 583 kb)