Additional file 3 of hsegHMM: hidden Markov model-based allele-specific copy number alteration analysis accounting for hypersegmentation Hyoyoung Choo-Wosoba Paul Albert Bin Zhu 10.6084/m9.figshare.7345385.v1 https://springernature.figshare.com/articles/journal_contribution/Additional_file_3_of_hsegHMM_hidden_Markov_model-based_allele-specific_copy_number_alteration_analysis_accounting_for_hypersegmentation/7345385 Figure S3. Allele-specific SCNA analysis based on the hsegHMM-N model of a simulated dataset for the simulation study with logR generated from normal-mixture distribution. The first two panels show the profiles of logR and logOR over the entire chromosomes; The last two panels indicate estimated copy numbers and genotype for each sequence over the entire chromosomes. (PDF 2407 kb) 2018-11-14 05:00:00 Allele-specific somatic copy number alteration Hidden Markov model Hypersegmentation Next-generation sequencing The cancer genome Atlas study