Additional file 5: of Loss of amphiregulin reduces myoepithelial cell coverage of mammary ducts and alters breast tumor growth
Serena Mao
Minji Park
Ramon Cabrera
John Christin
George Karagiannis
Maja Oktay
Dietmar Zaiss
Scott Abrams
Wenjun Guo
John Condeelis
Paraic Kenny
Jeffrey Segall
10.6084/m9.figshare.7262705.v1
https://springernature.figshare.com/articles/presentation/Additional_file_5_of_Loss_of_amphiregulin_reduces_myoepithelial_cell_coverage_of_mammary_ducts_and_alters_breast_tumor_growth/7262705
Figure S5 Loss of AREG is associated with increased vascular density in late-stage mammary tumors. (A) Representative images of CD31 staining of AREG+/+ PyMT and AREG−/− PyMT 1-cm tumors. (B) Compared to AREG+/+ PyMT tumors, more CD31+ vessels per field in AREG−/− PyMT tumors. Scale bar shows 100 μm. Statistical analyses performed using a t test. *p < 0.05, N = 3 (PPTX 182 kb)
2018-10-26 05:00:00
Amphiregulin
Mammary ductal development
MMTV-PyMT
Breast cancer