10.6084/m9.figshare.7262702.v1 Serena Mao Serena Mao Minji Park Minji Park Ramon Cabrera Ramon Cabrera John Christin John Christin George Karagiannis George Karagiannis Maja Oktay Maja Oktay Dietmar Zaiss Dietmar Zaiss Scott Abrams Scott Abrams Wenjun Guo Wenjun Guo John Condeelis John Condeelis Paraic Kenny Paraic Kenny Jeffrey Segall Jeffrey Segall Additional file 4: of Loss of amphiregulin reduces myoepithelial cell coverage of mammary ducts and alters breast tumor growth Springer Nature 2018 Amphiregulin Mammary ductal development MMTV-PyMT Breast cancer 2018-10-26 05:00:00 Presentation https://springernature.figshare.com/articles/presentation/Additional_file_4_of_Loss_of_amphiregulin_reduces_myoepithelial_cell_coverage_of_mammary_ducts_and_alters_breast_tumor_growth/7262702 Figure S4 Necrosis reduced in solid areas of AREG−/− PyMT tumors. Percentage necrosis in solid and papillary areas of AREG+/+ PyMT (N = 32) and AREG−/− PyMT (N = 22) tumors assessed individually. Significant differences observed between solid areas of AREG+/+ PyMT and AREG−/− PyMT tumors. In addition, papillary regions of both tumor genotypes have little to no necrosis. Statistical analysis performed using Mann–Whitney test. *p < 0.05, ***p < 0.001, ****P < 0.0001. n.s. not significant (PPTX 61 kb)