10.6084/m9.figshare.7210595.v1
Kelly Ceyzériat
Kelly
Ceyzériat
Lucile Ben Haim
Lucile
Ben Haim
Audrey Denizot
Audrey
Denizot
Dylan Pommier
Dylan
Pommier
Marco Matos
Marco
Matos
Océane Guillemaud
Océane
Guillemaud
Marie-Ange Palomares
Marie-Ange
Palomares
Laurene Abjean
Laurene
Abjean
Fanny Petit
Fanny
Petit
Pauline Gipchtein
Pauline
Gipchtein
Marie-Claude Gaillard
Marie-Claude
Gaillard
Martine Guillermier
Martine
Guillermier
Sueva Bernier
Sueva
Bernier
Mylène Gaudin
Mylène
Gaudin
Gwenaëlle Aurégan
Gwenaëlle
Aurégan
Charlène Joséphine
Charlène
Joséphine
Nathalie Déchamps
Nathalie
Déchamps
Julien Veran
Julien
Veran
Valentin Langlais
Valentin
Langlais
Karine Cambon
Karine
Cambon
Alexis Bemelmans
Alexis
Bemelmans
Jan Baijer
Jan
Baijer
Gilles Bonvento
Gilles
Bonvento
Marc Dhenain
Marc
Dhenain
Jean-François Deleuze
Jean-François
Deleuze
Stéphane Oliet
Stéphane
Oliet
Emmanuel Brouillet
Emmanuel
Brouillet
Philippe Hantraye
Philippe
Hantraye
Maria-Angeles Carrillo-de Sauvage
Maria-Angeles
Carrillo-de Sauvage
Robert Olaso
Robert
Olaso
Aude Panatier
Aude
Panatier
Carole Escartin
Carole
Escartin
Additional file 1: of Modulation of astrocyte reactivity improves functional deficits in mouse models of Alzheimer’s disease
Springer Nature
2018
Reactive astrocytes
Alzheimer’s disease
JAK2-STAT3 pathway
Signaling cascades
Viral vectors
Neuroinflammation
Mouse models
2018-10-16 05:00:00
Figure
https://springernature.figshare.com/articles/figure/Additional_file_1_of_Modulation_of_astrocyte_reactivity_improves_functional_deficits_in_mouse_models_of_Alzheimer_s_disease/7210595
Figure S1. AAV infect astrocytes selectively. To validate astrocyte tropism of the AAVs used in our study, an AAV2/9 encoding GFP was injected in the hippocampus of WT mice. GFP+ cells co-express the astrocytic marker GFAP and S100β, but not NeuN, IBA1, Olig2 and MBP, which are markers of neurons, microglial cells, cells of the oligodendrocyte lineage and myelinating oligodendrocytes, respectively. Astrocyte tropism of these vectors was confirmed in AD mice as well (See colocalization of GFP with GFAP in Figs. 1b and S2). (TIF 14477 kb)