10.6084/m9.figshare.7155674.v1
Kar-Tong Tan
Kar-Tong
Tan
Ling-Wen Ding
Ling-Wen
Ding
Qiao-Yang Sun
Qiao-Yang
Sun
Zhen-Tang Lao
Zhen-Tang
Lao
Wenwen Chien
Wenwen
Chien
Xi Ren
Xi
Ren
Jin-Fen Xiao
Jin-Fen
Xiao
Xin Loh
Xin
Loh
Liang Xu
Liang
Xu
Michael Lill
Michael
Lill
Anand Mayakonda
Anand
Mayakonda
De-Chen Lin
De-Chen
Lin
Henry Yang
Henry
Yang
H. Koeffler
H.
Koeffler
Additional file 1: of Profiling the B/T cell receptor repertoire of lymphocyte derived cell lines
Springer Nature
2018
BCR/TCR receptor repertoire
EBV lymphocytes
Cancer cell lines
2018-10-01 05:00:00
Dataset
https://springernature.figshare.com/articles/dataset/Additional_file_1_of_Profiling_the_B_T_cell_receptor_repertoire_of_lymphocyte_derived_cell_lines/7155674
Figure S1. Expression of CD19/CD20, CD79A/B and RAG1/RAG2 in blood cancer cell lines. X axis: 164 blood cancer cell lines grouped base on the disease types (rectangle color bar below the X axis), each dot in X axis represent one cell line, and the Y axis, expression level (log2 value) of indicated genes. Figure S2. Clonal fraction (filtered by >30 reads) of B-ALL, multiple myeloma, diffuse large B cell lymphoma, Burkitt lymphoma, B cell lymphoma (unspecified) and mantle cell lymphoma base on IGH or IGHK/L. Blue color indicates the clonotype fraction of the most dominant clone, Red color indicate the clonotype fraction of second dominant clone, Yellow color indicate the third dominant clone, while any smaller subclones were aggregated and labelled in grey. Figure S3. Clonal fraction (filtered by >30 reads) of T-ALL and anaplastic large cell lymphoma base on TRCA or TRCB. Blue color indicates the clonotype fraction of dominant clone, red color inidicate the clonotype fraction of second dominant clone, while gray color indicate the third dominant clone. Figure S4. Heatmap showing the usage of IGK/L V genes (A), IGK/L J genes (B), and constant region (C) in 462 samples of EBV transformed normal B lymphocytes. Figure S5. The phylogenetic tree inferred based on the rearrangement of the CDR3 region of IGH, IGK and IGL of EBV transformed B lymphocyte samples ERR188025, ERR188358 and ERR188212. These three cell lines have much higher number of rearrangement types than the other B lymphocyte lines. Clonal Fraction (upper panel) and the read counts (lower panel) of the dominant clone of 462 samples of EBV transformed normal B lymphocytes. (ZIP 1290 kb)