Human and mouse cistromes: genomic maps of putative cis-regulatory regions bound by transcription factors Ilya E. Vorontsov Alla D. Fedorova Ivan S. Yevshin Ruslan N. Sharipov Fedor A. Kolpakov Vsevolod J. Makeev Ivan V. Kulakovskiy 10.6084/m9.figshare.7087697.v1 https://springernature.figshare.com/articles/dataset/Human_and_mouse_cistromes_genomic_maps_of_putative_cis-regulatory_regions_bound_by_transcription_factors/7087697 <div>This dataset consists of 1 <b>.xlsx</b> file and 8 <b>.zip</b> files:</div><div>- <b>cistrome_overview.xlsx</b> is an Excel spreadsheet containing the computational protocol of the cistrome aggregation in the 1st tab, and overviews of the resulting cistrome maps for mouse and human in the 2nd and 3rd tabs.</div><div>- <b>cistrome_hg19.zip</b>, <b>cistrome_hg38.zip</b>, <b>cistrome_mm9.zip </b>and <b>cistrome_mm10.zip</b> contain genome-wide cistome genomic maps for human (hg19 and hg38) and mouse (mm9 and mm10) genome assemblies. Each <b>.zip</b> file contains two folders: one for the base cistrome and another for the motif-annotated subset. The contents of these folders are <b>.bed</b> files.</div><div>- <b>cistrome2genes_hg19.zip</b>, <b>cistrome2genes_hg38.zip</b>, <b>cistrome2genes_mm9.zip</b> and <b>cistrome2genes_mm10.zip</b> contain gene-centric maps for the respective human and mouse genome assemblies, annotated with the transcription start sites (TSS) using the GENCODE reference data. The gene lists include only the genes with cistrome regions located not farther than 10kb from TSS. These are <b>.tsv</b> files.</div><div>- Inside each <b>.zip</b> file, there is a separate text (<b>.txt</b>) file with a technical description of contents and file naming conventions.</div><div><br></div><div>The related manuscript describes the objectives, sourcing and processing of the data provided here in greater detail. In short, the objective is to present general genome-wide maps of putative cis-regulatory regions bound by transcription factors for human and mouse cistromes. This is achieved through systematic analysis of ChIP-Seq data obtained from the Gene Transcription Regulation Database (http://gtrd.biouml.org) and sequence motifs from the HOmo sapiens COmprehensive MOdel COllection (HOCOMOCO: http://hocomoco.autosome.ru).</div> 2018-10-17 15:22:24 human cistrome mouse cistrome transcription factors transcription factor binding sites ChIP-seq cistrome regulatory regions target genes human mouse Homo sapiens Mus musculus HOmo sapiens COmprehensive MOdel COllection Gene Transcription Regulation Database