10.6084/m9.figshare.6987806.v1 Haihan Jiao Haihan Jiao Matt Rutar Matt Rutar Nilisha Fernando Nilisha Fernando Ted Yednock Ted Yednock Sethu Sankaranarayanan Sethu Sankaranarayanan Riemke Aggio-Bruce Riemke Aggio-Bruce Jan Provis Jan Provis Riccardo Natoli Riccardo Natoli Additional file 2: of Subretinal macrophages produce classical complement activator C1q leading to the progression of focal retinal degeneration Springer Nature 2018 Macrophages Microglia Complement system Classical pathway C1q Inflammasome Retinal degeneration Photo-oxidative damage Inflammation Age-related macular degeneration 2018-08-20 05:00:00 Figure https://springernature.figshare.com/articles/figure/Additional_file_2_of_Subretinal_macrophages_produce_classical_complement_activator_C1q_leading_to_the_progression_of_focal_retinal_degeneration/6987806 Figure S2. Retinal C3d protein levels in wild-type (WT) dim-reared controls and after 7 days of photo-oxidative damage (PD). A: C3d protein levels significantly increased in retinas following 7 days of photo-oxidative damage (P < 0.05; N = 4). C3d levels were normalised to a GAPDH loading control. B-C: Representative western blots showing an increased level of C3d after 7 days of photo-oxidative damage (C) compared to dim-reared controls (B). Statistical significance was determined by an unpaired student t-test (* represents P < 0.05). (TIF 4344 kb)