Additional file 3: of High-flow nasal cannula oxygen therapy decreases postextubation neuroventilatory drive and work of breathing in patients with chronic obstructive pulmonary disease Di mussiRosa SpadaroSavino StripoliTania VoltaCarlo TrerotoliPaolo PierucciPaola StaffieriFrancesco BrunoFrancesco CamporotaLuigi GrassoSalvatore 2018 Independent sample t tests. Comparison between patients admitted for hypercapnic respiratory failure due to an exacerbation of COPD and patients with a background of COPD but whose hypercapnic respiratory failure was due to other precipitating causes in terms of EAdi parameters or work of breathing during each experimental condition. (DOCX 60 kb)