10.6084/m9.figshare.5932279.v1
Marija Sajic
Marija
Sajic
Keila Ida
Keila
Ida
Ryan Canning
Ryan
Canning
Norman Gregson
Norman
Gregson
Michael Duchen
Michael
Duchen
Kenneth Smith
Kenneth
Smith
Additional file 5: of Mitochondrial damage and âpluggingâ of transport selectively in myelinated, small-diameter axons are major early events in peripheral neuroinflammation
Springer Nature
2018
Experimental autoimmune neuritis (EAN)
Phototoxic damage
In vivo
Confocal imaging
Mitochondrial
Small axons
Pain
Neuropathy
2018-02-27 05:00:00
Media
https://springernature.figshare.com/articles/media/Additional_file_5_of_Mitochondrial_damage_and_plugging_of_transport_selectively_in_myelinated_small-diameter_axons_are_major_early_events_in_peripheral_neuroinflammation/5932279
Video S5. High-power time-lapse video of axonal mitochondria labeled with TMRM immediately following laser-induced phototoxic damage to mitochondria. The side of the imaging field left to the white line was not exposed to photo-toxic damage. The imaging field to the right of the white line was exposed to laser-induced photo-toxic damage, using the red laser to specifically damage functional mitochondria. Notably, the number of mobile mitochondria transported into the area exposed to photo-toxic damage appears overwhelmingly biased in the favor of anterograde movement. (AVI 2466Â kb)