10.6084/m9.figshare.5917804.v1 Panchanan Maiti Panchanan Maiti Leela Paladugu Leela Paladugu Gary Dunbar Gary Dunbar MOESM1 of Solid lipid curcumin particles provide greater anti-amyloid, anti-inflammatory and neuroprotective effects than curcumin in the 5xFAD mouse model of Alzheimer’s disease Springer Nature 2018 Alzheimer’s disease Neurodegeneration Neuroinflammation Curcumin Amyloid beta protein Anti-amyloid 2018-02-23 05:00:00 Journal contribution https://springernature.figshare.com/articles/journal_contribution/MOESM1_of_Solid_lipid_curcumin_particles_provide_greater_anti-amyloid_anti-inflammatory_and_neuroprotective_effects_than_curcumin_in_the_5xFAD_mouse_model_of_Alzheimer_s_disease/5917804 Additional file 1: Fig. S1. Comparative solubility and permeability of Cur or SLCP in vitro. A: schematic diagram of formulation of SLCP. Upper row: Solubility of Cur and SLCP in PBS. Note SLCP appeared to be more soluble in PBS, whereas Cur predominantly formed crystal-like structures. Middle and lower rows: The SLCP appeared to confer greater permeability than Cur in both N2a and 7-DIV primary hippocampal neurons after 2 h of incubation.