Additional file 4: Figure S4. of Role of the indoleamine-2,3-dioxygenase/kynurenine pathway of tryptophan metabolism in behavioral alterations in a hepatic encephalopathy rat model Xi Jiang Lexing Xu Lin Tang Fuhe Liu Ziwei Chen Jiajia Zhang Lei Chen Cong Pang Xuefeng Yu 10.6084/m9.figshare.5759013.v1 https://springernature.figshare.com/articles/figure/Additional_file_4_Figure_S4_of_Role_of_the_indoleamine-2_3-dioxygenase_kynurenine_pathway_of_tryptophan_metabolism_in_behavioral_alterations_in_a_hepatic_encephalopathy_rat_model/5759013 Effects of IDO inhibitor 1-MT (1, 3 mg/kg) on KYN/TRY ratio in the hippocampus (A) and cerebral cortex (B), and 5-HT/TRY ratio in the hippocampus (C) and cerebral cortex (D) of BDL rats. Data are expressed as mean ± SEM (n = 6). *p < 0.05, **p < 0.01 and ***p < 0.001 when compared to the sham group, #p < 0.05 when compared to the BDL group. (TIFF 3600 kb) 2018-01-04 05:00:00 Hepatic encephalopathy (HE) Inflammation Indoleamine-2,3-dioxygenase (IDO) Serotonin (5-HT) Depression Anxiety