Additional file 2: of Spectrum of mutations in monogenic diabetes genes identified from high-throughput DNA sequencing of 6888 individuals Vikas Bansal Johann Gassenhuber Tierney Phillips Glenn Oliveira Rebecca Harbaugh Nikki Villarasa Eric Topol Thomas Seufferlein Bernhard Boehm 10.6084/m9.figshare.5674108.v1 https://springernature.figshare.com/articles/journal_contribution/Additional_file_2_of_Spectrum_of_mutations_in_monogenic_diabetes_genes_identified_from_high-throughput_DNA_sequencing_of_6888_individuals/5674108 Supplementary Methods: Description of methods for pooled variant calling, gene-level tests for rare coding variants, statistical analyses, comparison of pooled sequence data with population exome data, comparison of pooled allele counts with individual genotypes, and identification of the carriers of rare variants. (PDF 671 kb) 2017-12-06 05:00:00 High-throughput sequencing Monogenic diabetes Pathogenic variants Type 2 diabetes MODY DNA pooling Targeted sequencing