10.6084/m9.figshare.c.3926998_D1.v1 Sharmeen Chagani Sharmeen Chagani Rong Wang Rong Wang Evan Carpenter Evan Carpenter Christiane Löhr Christiane Löhr Gitali Ganguli-Indra Gitali Ganguli-Indra Arup Indra Arup Indra Additional file 1: Figure S1. of Ablation of epidermal RXRα in cooperation with activated CDK4 and oncogenic NRAS generates spontaneous and acute neonatal UVB induced malignant metastatic melanomas Springer Nature 2017 Keratinocytes Melanocytes Acute UVB Retinoid-X-receptor α (RXRα) Malignant melanoma Trigenic Spontaneous melanoma NRASQ61K CDK4R24C/R24C Microenvironment 2017-11-09 05:00:00 Figure https://springernature.figshare.com/articles/figure/Additional_file_1_Figure_S1_of_Ablation_of_epidermal_RXR_in_cooperation_with_activated_CDK4_and_oncogenic_NRAS_generates_spontaneous_and_acute_neonatal_UVB_induced_malignant_metastatic_melanomas/5589520 Breeding of mouse lines and UV scheme used in this study. (a) Breeding crossings used. K14-Cretg/O I RxrαL2/L2 is also known as Rxrαep−/−. (b) Scheme for single neonatal UVB treatment of mice. (c) H&E stained section showing poorly differentiated melanoma with abnormally large nuclei compared to the normal range (inset). (TIFF 1999 kb)