Additional file 2: of Direct conversion of human fibroblasts to functional excitatory cortical neurons integrating into human neural networks
Giedre Miskinyte
Karthikeyan Devaraju
Marita Grønning Hansen
Emanuela Monni
Daniel Tornero
Niels Woods
Johan Bengzon
Henrik Ahlenius
Olle Lindvall
Zaal Kokaia
10.6084/m9.figshare.c.3893248_D2.v1
https://springernature.figshare.com/articles/media/Additional_file_2_of_Direct_conversion_of_human_fibroblasts_to_functional_excitatory_cortical_neurons_integrating_into_human_neural_networks/5457766
Three-dimensional video reconstruction of iCtx cell ex vivo transplanted onto adult human-derived cortical tissue. Fly-through animation of three-dimensional data illustrating pyramidal shape of iCtx cell (in red) with elaborated neurites extending throughout the whole depth of the adult human cortical slice at 3Â weeks after ex vivo transplantation. Note many spines of different size and shape including mushroom-like ones. Many Hoechst-stained cell nuclei of human cortex (in blue) are distributed throughout the slice. Scale bar in left bottom corner. (MOV 16146 kb)
2017-09-29 05:00:00
Cortical projection neurons
Direct conversion
Human adult cortical slices
Human fibroblasts