Additional file 2: of Direct conversion of human fibroblasts to functional excitatory cortical neurons integrating into human neural networks Giedre Miskinyte Karthikeyan Devaraju Marita Grønning Hansen Emanuela Monni Daniel Tornero Niels Woods Johan Bengzon Henrik Ahlenius Olle Lindvall Zaal Kokaia 10.6084/m9.figshare.c.3893248_D2.v1 https://springernature.figshare.com/articles/media/Additional_file_2_of_Direct_conversion_of_human_fibroblasts_to_functional_excitatory_cortical_neurons_integrating_into_human_neural_networks/5457766 Three-dimensional video reconstruction of iCtx cell ex vivo transplanted onto adult human-derived cortical tissue. Fly-through animation of three-dimensional data illustrating pyramidal shape of iCtx cell (in red) with elaborated neurites extending throughout the whole depth of the adult human cortical slice at 3 weeks after ex vivo transplantation. Note many spines of different size and shape including mushroom-like ones. Many Hoechst-stained cell nuclei of human cortex (in blue) are distributed throughout the slice. Scale bar in left bottom corner. (MOV 16146 kb) 2017-09-29 05:00:00 Cortical projection neurons Direct conversion Human adult cortical slices Human fibroblasts