10.6084/m9.figshare.c.3872092_D2.v1
José Rivera
José
Rivera
Baraa Noueihed
Baraa
Noueihed
Ankush Madaan
Ankush
Madaan
Isabelle Lahaie
Isabelle
Lahaie
Jingyi Pan
Jingyi
Pan
Jaques Belik
Jaques
Belik
Sylvain Chemtob
Sylvain
Chemtob
Additional file 2: Figure S2. of Tetrahydrobiopterin (BH4) deficiency is associated with augmented inflammation and microvascular degeneration in the retina
Springer Nature
2017
Tetrahydrobiopterin
BH4
Microvascular degeneration
Thrombospondin-1
Inflammation
Microglia
2017-09-06 05:00:00
Journal contribution
https://springernature.figshare.com/articles/journal_contribution/Additional_file_2_Figure_S2_of_Tetrahydrobiopterin_BH4_deficiency_is_associated_with_augmented_inflammation_and_microvascular_degeneration_in_the_retina/5379067
Tetrahydrobiopterin (BH4) content in hph-1 mice at early ages. BH4 content (ng/mg of tissue) in retinas from control (WT) and hph-1 mice at postnatal day 7 and 14 (P7 and P14) was measured by using liquid chromatography tandem mass spectrometry (LC-MS/MS). The levels of BH4 were significantly decreased by ~ 90% in the retinas of hph-1 at P7 and P14 compared with WT mice. Results showed in the histograms are expressed as means ± SEM of n = 5 mice for each group. **p < 0.005 and ***p < 0.0001 compared to control. (PDF 109 kb)