10.6084/m9.figshare.c.3872092_D2.v1 José Rivera José Rivera Baraa Noueihed Baraa Noueihed Ankush Madaan Ankush Madaan Isabelle Lahaie Isabelle Lahaie Jingyi Pan Jingyi Pan Jaques Belik Jaques Belik Sylvain Chemtob Sylvain Chemtob Additional file 2: Figure S2. of Tetrahydrobiopterin (BH4) deficiency is associated with augmented inflammation and microvascular degeneration in the retina Springer Nature 2017 Tetrahydrobiopterin BH4 Microvascular degeneration Thrombospondin-1 Inflammation Microglia 2017-09-06 05:00:00 Journal contribution https://springernature.figshare.com/articles/journal_contribution/Additional_file_2_Figure_S2_of_Tetrahydrobiopterin_BH4_deficiency_is_associated_with_augmented_inflammation_and_microvascular_degeneration_in_the_retina/5379067 Tetrahydrobiopterin (BH4) content in hph-1 mice at early ages. BH4 content (ng/mg of tissue) in retinas from control (WT) and hph-1 mice at postnatal day 7 and 14 (P7 and P14) was measured by using liquid chromatography tandem mass spectrometry (LC-MS/MS). The levels of BH4 were significantly decreased by ~ 90% in the retinas of hph-1 at P7 and P14 compared with WT mice. Results showed in the histograms are expressed as means ± SEM of n = 5 mice for each group. **p < 0.005 and ***p < 0.0001 compared to control. (PDF 109 kb)