%0 DATA
%A Svenja, Schüler
%A Meinhard, Kieser
%A Geraldine, Rauch
%D 2017
%T Additional file 4 of Choice of futility boundaries for group sequential designs with two endpoints
%U https://springernature.figshare.com/articles/Additional_file_4_of_Choice_of_futility_boundaries_for_group_sequential_designs_with_two_endpoints/5287804
%R 10.6084/m9.figshare.c.3846742_D4.v1
%2 https://springernature.figshare.com/ndownloader/files/9057742
%K Group sequential design
%K Stopping for futility
%K Two endpoints
%K Intersection-union test
%X Probability of stopping for futility and overall power for Approach 3. Plot of probability of stopping for futility (left figure) and overall power (right figure) for Approach 3 using the futility β γ-boundaries α f CE = 0.69 $ \alpha_{f}^{CE}=0.69$ and α f MC = 0.65 $ \alpha_{f}^{MC}=0.65$ for composite endpoint and main component, respectively. (JPG 202 kb)