%0 Figure %A Schüler, Svenja %A Kieser, Meinhard %A Rauch, Geraldine %D 2017 %T Additional file 3 of Choice of futility boundaries for group sequential designs with two endpoints %U https://springernature.figshare.com/articles/figure/Additional_file_3_of_Choice_of_futility_boundaries_for_group_sequential_designs_with_two_endpoints/5287786 %R 10.6084/m9.figshare.c.3846742_D3.v1 %2 https://springernature.figshare.com/ndownloader/files/9057721 %K Group sequential design %K Stopping for futility %K Two endpoints %K Intersection-union test %X Probability of stopping for futility and overall power for Approach 2. Plot of probability of stopping for futility (left figure) and overall power (right figure) for Approach 2 using the futility β γ-boundaries α f CE = 0.65 $ \alpha_{f}^{CE}=0.65$ and α f MC = 0.37 $ \alpha_{f}^{MC}=0.37$ for composite endpoint and main component, respectively. (JPG 238 kb) %I figshare