Additional file 1: of The role of alternative Polyadenylation in regulation of rhythmic gene expression Natalia Ptitsyna Sabri Boughorbel Mohammed El Anbari Andrey Ptitsyn 10.6084/m9.figshare.c.3844486_D1.v1 https://springernature.figshare.com/articles/journal_contribution/Additional_file_1_of_The_role_of_alternative_Polyadenylation_in_regulation_of_rhythmic_gene_expression/5280508 Supplemental method. In addition to Chi-Square test summarized in Table 1 we run a Monte Carlo simulation with 1000 repetitions with the option simulate.p.value as described in https://stat.ethz.ch/R-manual/R-devel/library/stats/html/chisq.test.html . This supplemental file provides description and p-values obtained in simulations. (DOCX 10 kb) 2017-08-04 05:00:00 Alternative transcription Oscillatory gene expression Cellular circuits Molecular diode, mathematical modeling, datamining