10.6084/m9.figshare.c.3842200_D3.v1
Sylvia Torres-Odio
Sylvia
Torres-Odio
Jana Key
Jana
Key
Hans-Hermann Hoepken
Hans-Hermann
Hoepken
Júlia Canet-Pons
Júlia
Canet-Pons
Lucie Valek
Lucie
Valek
Bastian Roller
Bastian
Roller
Michael Walter
Michael
Walter
Blas Morales-Gordo
Blas
Morales-Gordo
David Meierhofer
David
Meierhofer
Patrick Harter
Patrick
Harter
Michel Mittelbronn
Michel
Mittelbronn
Irmgard Tegeder
Irmgard
Tegeder
Suzana Gispert
Suzana
Gispert
Georg Auburger
Georg
Auburger
Additional file 1: Table S1. of Progression of pathology in PINK1-deficient mouse brain from splicing via ubiquitination, ER stress, and mitophagy changes to neuroinflammation
Springer Nature
2017
Parkinson’s disease
Ubiquitin kinase PINK1
Mitochondrial dysfunction
Antiviral response
Neuroinflammation
2017-08-02 05:00:00
Dataset
https://springernature.figshare.com/articles/dataset/Additional_file_1_Table_S1_of_Progression_of_pathology_in_PINK1-deficient_mouse_brain_from_splicing_via_ubiquitination_ER_stress_and_mitophagy_changes_to_neuroinflammation/5271247
Global transcriptome profile of Pink1 −/− brain regions (C = cerebellum, M = midbrain, S = striatum) across the mouse lifespan (6 W = 6 weeks, 24 W = 24 weeks = 6 months, 18 M = 18 months), showing all expression dysregulations which were consistent in all regions at all ages with significance (multiple testing adjusted p value <0.05). ID identifies the Affymetrix microarray chip probe. AveExpr quantifies the average expression strength among the tissues and ages for each transcript. F, P value, and AdjPvalue refer to statistical values. For each column, 3 mutant versus 3 WT tissues were analyzed to represent a specific brain region and age. (XLS 27 kb)