%0 Figure %A Lukhele, Sabelo %A Cohen, Éric %D 2017 %T MOESM1 of Conserved residues within the HIV-1 Vpu transmembrane-proximal hinge region modulate BST2 binding and antagonism %U https://springernature.figshare.com/articles/figure/MOESM1_of_Conserved_residues_within_the_HIV-1_Vpu_transmembrane-proximal_hinge_region_modulate_BST2_binding_and_antagonism/4750372 %R 10.6084/m9.figshare.c.3716173_D1.v1 %2 https://springernature.figshare.com/ndownloader/files/7789852 %K HIV-1 Vpu %K BST2 antagonism %K Vpu–BST2 interaction %K Vpu–BST2 trafficking %K Vpu–CD4 interaction %X Additional file 1: Figure S1. Ability of Vpu mutants to mediate BST2 degradation. Shown is a representative Western blot indicating the steady state levels of BST2 in mock-infected HeLa cells (lane 1) as well as in Hela cells following infections with VSV-G-pseudotyped HIV-1 viruses encoding WT Vpu and the indicated Vpu mutants (lanes 2–7). Analysis of BST2 expression in BST2-depleted HeLa cells is also shown in lane 8. Below the blot is the extent of BST2 expression based on densitometric analyses of the intensities of BST2-related band signals obtained from each Vpu mutant, relative to dU (set at 100%). %I figshare