MOESM10 of SMYD5 regulates H4K20me3-marked heterochromatin to safeguard ES cell self-renewal and prevent spurious differentiation
Benjamin Kidder
Gangqing Hu
Kairong Cui
Keji Zhao
10.6084/m9.figshare.c.3701899_D3.v1
https://springernature.figshare.com/articles/journal_contribution/MOESM10_of_SMYD5_regulates_H4K20me3-marked_heterochromatin_to_safeguard_ES_cell_self-renewal_and_prevent_spurious_differentiation/4689247
Additional file 10: Figure S10. Decreased H3K9me3 heterochromatin foci in SMYD5-depleted ES cells. (A, B) Immunofluorescence staining of H3K9me3 in (A) shLuc and (B) shSmyd5 ES cells. Nuclei were stained with DAPI. (C) Quantitation of nuclear H3K9me3 heterochromatin foci using ImageJ software.
2017-02-23 05:00:00
Embryonic stem cells
SMYD5
H4K20me3
Repetitive DNA
LTR
LINE
Pluripotent
Epigenetics
Chromatin
Heterochromatin
Genomics
RNA-Seq
ChIP-Seq
Self-renewal
Gene expression
Embryoid body
Differentiation
Histone methyltransferase