Additional file 3: Figure S3. of Involvement of Ubiquitin-Editing Protein A20 in Modulating Inflammation in Rat Cochlea Associated with Silver Nanoparticle-Induced CD68 Upregulation and TLR4 Activation
Hao Feng
Ilmari Pyykkö
Jing Zou
10.6084/m9.figshare.c.3698866_D4.v1
https://springernature.figshare.com/articles/figure/Additional_file_3_Figure_S3_of_Involvement_of_Ubiquitin-Editing_Protein_A20_in_Modulating_Inflammation_in_Rat_Cochlea_Associated_with_Silver_Nanoparticle-Induced_CD68_Upregulation_and_TLR4_Activation/4675678
MCP2+ cells in the rat cochlea 7 days post-intratympanic injection of 0.4 % AgNPs shown by immunofluorescence confocal microscopy or immunohistochemistry. In the cochleae exposed to dH2O, the strial basal cells (SBCs), spiral ligament fibrocytes (SLFs), spiral ganglion cells (SGCs), and hair cells (HCs), pillar cells (PCs), and Deiters’ cells (DCs) of Corti’s organ (CO) showed intensive staining (B, D, and F). 0.4 % AgNPs had no influence on the staining in the SBCs, SLFs, SGCs, and CO (A, C, and E). Comparisons of staining intensity are shown in G and H. Scale bar = 50 μm in A–D and 20 μm in E and F. (JPG 4614 kb)
2016-05-04 05:00:00
rat cochlea 7 days post-intratympanic injection
hair cells
dH 2O
HC
JPG 4614 kb
strial basal cells
PC
Ubiquitin-Editing Protein
20 μ
20 μ m
TLR
CO
Rat Cochlea Associated
immunofluorescence confocal microscopy
SBC
DC
Silver Nanoparticle-Induced CD 68 Upregulation
SGC
SLF
Modulating Inflammation
staining intensity
MCP