Additional file 1: Table S1. of
SPAG6 and L1TD1 are transcriptionally regulated by DNA methylation in non-small cell lung cancers
Corinna Altenberger
Gerwin Heller
Barbara Ziegler
Erwin Tomasich
Maximilian Marhold
Thais Topakian
Leonhard Müllauer
Petra Heffeter
György Lang
Adelheid End-Pfützenreuter
Balazs Döme
Britt-Madeleine Arns
Walter Klepetko
Christoph Zielinski
Sabine Zöchbauer-Müller
10.6084/m9.figshare.c.3697522_D4.v1
https://springernature.figshare.com/articles/journal_contribution/Additional_file_1_Table_S1_of___SPAG6_and_L1TD1_are_transcriptionally_regulated_by_DNA_methylation_in_non-small_cell_lung_cancers/4673167
Description of NSCLC cell lines used in this study. Information about histology, origin and disease stage of donors was obtained from ATCC catalogue ( https://www.lgcstandards-atcc.org ). EGFR, KRAS and TP53 mutational status and MET amplification according to supplementary references (1–3). *activating EGFR mutation in exon 19 (E746-E749 del), **activating EGFR mutation in exon 21 (L858R). N/A, not available; wt, wildtype; mut, mutated. Table S2. Clinico-pathological characteristics of 983 NSCLC patients. Overview of gender, histology, stage of disease and ethnicity of NSCLC patients obtained from TCGA database and used for mutation and copy number changes analyses of SPAG6 and L1TD1 is shown. ADC, adenocarcinoma; SCC, squamous cell carcinoma. Clinical data based on Caleydo software version 16/04/14. Table S3. Primer sequences. Summary of oligonucleotide sequences used for mRNA expression, MS-HRM, BGS analyses and construction of pCMV6-GFP expression vector. Y, random integration of C or T in fwd primer; R, random integration of G or A in rev primer. Table S4. Methylation of SPAG6 and L1TD1 in tumor cells of other tumor types. *Morphology, histology and origin of cell lines according to ATCC catalogue ( https://www.lgcstandards-atcc.org ). Percentage of methylation was calculated as described previously (4). (DOCX 33 kb)
2017-01-05 05:00:00
Epigenetics
DNA methylation
Non-small cell lung cancer
SPAG6
L1TD1