Additional file 8: Figure S5. of Epithelial response to a high-protein diet in rat colon Martin Beaumont Mireille Andriamihaja Lucie Armand Marta Grauso Florence Jaffrézic Denis Laloë Marco Moroldo Anne-Marie Davila Daniel Tomé François Blachier Annaïg Lan 10.6084/m9.figshare.c.3677791_D6.v1 https://springernature.figshare.com/articles/journal_contribution/Additional_file_8_Figure_S5_of_Epithelial_response_to_a_high-protein_diet_in_rat_colon/4597465 Tight-junction signaling canonical pathway diagram. This pathway was significantly enriched in the set of genes regulated by the high-protein diet. The diagram was obtained from Ingenuity Pathway Analysis software and depicts genes implicated in this pathway and their interactions. Expression of genes colored in green were downregulated (q < 0.1) in colonocytes of rats fed a high-protein diet when compared to a normal-protein diet. (PDF 465 kb) 2017-01-31 05:00:00 Epithelial cells Colon Dietary protein High-protein diet Transcriptome DNA damages Barrier function Mucus Epithelial renewal