Paul, Dirk Jones, Allison Sellar, Rob Mayor, Neema Feber, Andrew Webster, Amy Afonso, Neuza Sergeant, Ruhena Szydlo, Richard Apperley, Jane Widschwendter, Martin Mackinnon, Stephen Marsh, Steven Madrigal, J. Rakyan, Vardhman Peggs, Karl Beck, Stephan Additional file 6: of A donor-specific epigenetic classifier for acute graft-versus-host disease severity in hematopoietic stem cell transplantation Box-and-whisker plots of DNA methylation values in graft donors in the discovery cohort assessed using MethyLight and 450K arrays. Only HSCT donors of the discovery cohort that were profiled on both assay platforms are shown. We identified a DNA hypomethylation phenotype at the top-ranked DMP cg20475486 in graft donors matched to recipients with severe aGVHD. HSCT donors matched to healthy recipients and those matched to recipients diagnosed with mild aGVHD could not be discriminated. (PDF 256 kb) discovery cohort;PDF 256 kb;DNA hypomethylation phenotype;graft donors;DMP cg 20475486;aGVHD;DNA methylation values;cell transplantation Box-and-whisker plots;recipient;HSCT donors;graft-versus-host disease severity;450 K arrays 2015-12-15
    https://springernature.figshare.com/articles/journal_contribution/Additional_file_6_of_A_donor-specific_epigenetic_classifier_for_acute_graft-versus-host_disease_severity_in_hematopoietic_stem_cell_transplantation/4454738
10.6084/m9.figshare.c.3640241_D1.v1