10.6084/m9.figshare.c.3637409_D2.v1
Ahmed Abdelbaset-Ismail
Ahmed
Abdelbaset-Ismail
Daniel Pedziwiatr
Daniel
Pedziwiatr
Ewa Suszyńska
Ewa
Suszyńska
Sylwia Sluczanowska-Glabowska
Sylwia
Sluczanowska-Glabowska
Gabriela Schneider
Gabriela
Schneider
Sham Kakar
Sham
Kakar
Mariusz Ratajczak
Mariusz
Ratajczak
Additional file 2: Figure S2. of Vitamin D3 stimulates embryonic stem cells but inhibits migration and growth of ovarian cancer and teratocarcinoma cell lines
Springer Nature
2016
Vitamin D3
VDR
Germline tumors
Ovarian cancer
Teratocarcinoma
VSELs
2016-04-18 05:00:00
Presentation
https://springernature.figshare.com/articles/presentation/Additional_file_2_Figure_S2_of_Vitamin_D3_stimulates_embryonic_stem_cells_but_inhibits_migration_and_growth_of_ovarian_cancer_and_teratocarcinoma_cell_lines/4444604
1,25-dihydroxyvitamin D3 induces proliferation of quiescent BM-derived very small embryonic-like stem cells (VSELs) in vivo. Panel A. After treatment with 1,25-dihydroxyvitamin D3, as shown here, no significant difference in BrdU-incorporated HSCs was observed in treated and control animals (6 male mice/group). Panel B. BrdU incorporation into VSELs after 1,25-dihydroxyvitamin D3 treatment. The percentages of VSELs that incorporated BrdU into newly synthesized DNA. After treatment with 1,25-dihydroxyvitamin D3 at 800 IU/dose, ~13.2 % of VSELs were BrdU+, in contrast to the control group in which ~7 % of VSELs were BrdU+ (6 male mice/group). The incorporation of BrdU into HSCs and VSELs was measured by FACS. (PPT 100 kb)