10.6084/m9.figshare.c.3637409_D2.v1 Ahmed Abdelbaset-Ismail Ahmed Abdelbaset-Ismail Daniel Pedziwiatr Daniel Pedziwiatr Ewa Suszyńska Ewa Suszyńska Sylwia Sluczanowska-Glabowska Sylwia Sluczanowska-Glabowska Gabriela Schneider Gabriela Schneider Sham Kakar Sham Kakar Mariusz Ratajczak Mariusz Ratajczak Additional file 2: Figure S2. of Vitamin D3 stimulates embryonic stem cells but inhibits migration and growth of ovarian cancer and teratocarcinoma cell lines Springer Nature 2016 Vitamin D3 VDR Germline tumors Ovarian cancer Teratocarcinoma VSELs 2016-04-18 05:00:00 Presentation https://springernature.figshare.com/articles/presentation/Additional_file_2_Figure_S2_of_Vitamin_D3_stimulates_embryonic_stem_cells_but_inhibits_migration_and_growth_of_ovarian_cancer_and_teratocarcinoma_cell_lines/4444604 1,25-dihydroxyvitamin D3 induces proliferation of quiescent BM-derived very small embryonic-like stem cells (VSELs) in vivo. Panel A. After treatment with 1,25-dihydroxyvitamin D3, as shown here, no significant difference in BrdU-incorporated HSCs was observed in treated and control animals (6 male mice/group). Panel B. BrdU incorporation into VSELs after 1,25-dihydroxyvitamin D3 treatment. The percentages of VSELs that incorporated BrdU into newly synthesized DNA. After treatment with 1,25-dihydroxyvitamin D3 at 800 IU/dose, ~13.2 % of VSELs were BrdU+, in contrast to the control group in which ~7 % of VSELs were BrdU+ (6 male mice/group). The incorporation of BrdU into HSCs and VSELs was measured by FACS. (PPT 100 kb)