Chen, Tenghui Wang, Zixing Zhou, Wanding Chong, Zechen Meric-Bernstam, Funda Mills, Gordon Chen, Ken Additional file 10: Figure S5. of Hotspot mutations delineating diverse mutational signatures and biological utilities across cancer types Functional implications of hotspot mutations in RNA and protein expression. In OV, tumor samples with missense hotspot mutations (I195, Y220, R248 and R273) in TP53 show higher TP53 RNA and protein expression than those with non-hotspot mutations and without TP53 mutations. * indicates p < 0.05 and ** indicates p < 0.001 between samples with specified hotspot mutations and samples with non-hotspot mutations in examined gene; # indicates p < 0.05 and ## indicates p < 0.001 between samples with specified hotspot mutations and samples without mutations in examined gene. (PDF 365 kb) sample;TP 53 show;cancer types Functional implications;TP 53 mutations;TP 53 RNA;PDF 365 kb;hotspot mutations;missense hotspot mutations;protein expression;OV;non-hotspot mutations 2016-06-23
    https://springernature.figshare.com/articles/journal_contribution/Additional_file_10_Figure_S5_of_Hotspot_mutations_delineating_diverse_mutational_signatures_and_biological_utilities_across_cancer_types/4435886
10.6084/m9.figshare.c.3634619_D3.v1