Deming, Yuetiva Black, Kathleen Carrell, David Cai, Yefei Del-Aguila, Jorge Fernandez, Maria Budde, John Ma, ShengMei Saef, Benjamin Howells, Bill Bertelsen, Sarah Huang, Kuan-lin Sutphen, Courtney Tarawneh, Rawan Fagan, Anne Holtzman, David Morris, John Goate, Alison Dougherty, Joseph Cruchaga, Carlos Additional file 2: of Chitinase-3-like 1 protein (CHI3L1) locus influences cerebrospinal fluid levels of YKL-40 Supplementary Methods and Results. Methods and results for the gene ontology over-representation analyses of top SNPs from the single variant analysis of CSF YKL-40 levels. 70 genes mapped to the top SNPs (p < 1 × 10-4) were significantly enriched in human brain and pituitary tissue at all levels of specificity. Figure illustrates the different human tissues with expression data available with Benjamini-Hochberg corrected p < 0.10 in the enrichment analysis and the Table shows the results for all tissues with uncorrected p < 0.05 in at least one specificity index. The specificity index represents how specific a set of genes are to a particular tissue. (DOCX 163 kb) CHI3L1;YKL-40;Cerebrospinal fluid;Alzheimer disease 2016-11-10
    https://springernature.figshare.com/articles/journal_contribution/Additional_file_2_of_Chitinase-3-like_1_protein_CHI3L1_locus_influences_cerebrospinal_fluid_levels_of_YKL-40/4427045
10.6084/m9.figshare.c.3632078_D2.v1