%0 Journal Article %A Deming, Yuetiva %A Black, Kathleen %A Carrell, David %A Cai, Yefei %A Del-Aguila, Jorge %A Fernandez, Maria %A Budde, John %A Ma, ShengMei %A Saef, Benjamin %A Howells, Bill %A Bertelsen, Sarah %A Huang, Kuan-lin %A Sutphen, Courtney %A Tarawneh, Rawan %A Fagan, Anne %A Holtzman, David %A Morris, John %A Goate, Alison %A Dougherty, Joseph %A Cruchaga, Carlos %D 2016 %T Additional file 2: of Chitinase-3-like 1 protein (CHI3L1) locus influences cerebrospinal fluid levels of YKL-40 %U https://springernature.figshare.com/articles/journal_contribution/Additional_file_2_of_Chitinase-3-like_1_protein_CHI3L1_locus_influences_cerebrospinal_fluid_levels_of_YKL-40/4427045 %R 10.6084/m9.figshare.c.3632078_D2.v1 %2 https://springernature.figshare.com/ndownloader/files/7153685 %K CHI3L1 %K YKL-40 %K Cerebrospinal fluid %K Alzheimer disease %X Supplementary Methods and Results. Methods and results for the gene ontology over-representation analyses of top SNPs from the single variant analysis of CSF YKL-40 levels. 70 genes mapped to the top SNPs (p < 1 × 10-4) were significantly enriched in human brain and pituitary tissue at all levels of specificity. Figure illustrates the different human tissues with expression data available with Benjamini-Hochberg corrected p < 0.10 in the enrichment analysis and the Table shows the results for all tissues with uncorrected p < 0.05 in at least one specificity index. The specificity index represents how specific a set of genes are to a particular tissue. (DOCX 163 kb) %I figshare