Additional file 4: Figure S1. of DNA hypomethylation of Synapsin II CpG islands associates with increased gene expression in bipolar disorder and major depression
Cristiana Cruceanu
Elena Kutsarova
Elizabeth Chen
David Checknita
Corina Nagy
Juan Lopez
Martin Alda
Guy Rouleau
Gustavo Turecki
10.6084/m9.figshare.c.3628775_D3.v1
https://springernature.figshare.com/articles/presentation/Additional_file_4_Figure_S1_of_DNA_hypomethylation_of_Synapsin_II_CpG_islands_associates_with_increased_gene_expression_in_bipolar_disorder_and_major_depression/4416980
DNA methylation (percent values) at significant individual CpGs. A-E. Scatter plots represent individual % methylation values for each of the 5 loci found to be significant for at least one diagnostic group (marked with * in Fig. 1) by Least Significant Difference (LSD) post-hoc analyses. F. Average % methylation for the three consequent CpGs shown to be significantly different in MDD compared to CTRL by Least Significant Difference (LSD) post-hoc analyses. The average values were found to be significantly different between the groups (Student’s T-Test, p-value = 0.03). (PPTX 354 kb)
2016-08-11 05:00:00
Bipolar disorder
Major depressive disorder
DNA Methylation
Epigenetics
Mood disorders