Additional file 4: Figure S1. of DNA hypomethylation of Synapsin II CpG islands associates with increased gene expression in bipolar disorder and major depression Cristiana Cruceanu Elena Kutsarova Elizabeth Chen David Checknita Corina Nagy Juan Lopez Martin Alda Guy Rouleau Gustavo Turecki 10.6084/m9.figshare.c.3628775_D3.v1 https://springernature.figshare.com/articles/presentation/Additional_file_4_Figure_S1_of_DNA_hypomethylation_of_Synapsin_II_CpG_islands_associates_with_increased_gene_expression_in_bipolar_disorder_and_major_depression/4416980 DNA methylation (percent values) at significant individual CpGs. A-E. Scatter plots represent individual % methylation values for each of the 5 loci found to be significant for at least one diagnostic group (marked with * in Fig. 1) by Least Significant Difference (LSD) post-hoc analyses. F. Average % methylation for the three consequent CpGs shown to be significantly different in MDD compared to CTRL by Least Significant Difference (LSD) post-hoc analyses. The average values were found to be significantly different between the groups (Student’s T-Test, p-value = 0.03). (PPTX 354 kb) 2016-08-11 05:00:00 Bipolar disorder Major depressive disorder DNA Methylation Epigenetics Mood disorders