%0 Journal Article %A Baumann, Jan %A Wong, Jason %A Sun, Yan %A Conklin, Douglas %D 2016 %T Additional file 1: Figure S1. of Palmitate-induced ER stress increases trastuzumab sensitivity in HER2/neu-positive breast cancer cells %U https://springernature.figshare.com/articles/journal_contribution/Additional_file_1_Figure_S1_of_Palmitate-induced_ER_stress_increases_trastuzumab_sensitivity_in_HER2_neu-positive_breast_cancer_cells/4416914 %R 10.6084/m9.figshare.c.3628757_D1.v1 %2 https://springernature.figshare.com/ndownloader/files/7143332 %K HER2/neu %K ERBB2 %K Metabolism %K Palmitate %K Trastuzumab %K ER stress %K Saturated fat %K High fat diet %X Addition of exogenous palmitate does not increase cellular permeability of SKBR3 cells. Figure S2: Detailed results of the GO-term enrichment analysis for MCF7 cells using the DAVID Bioinformatics resource. Figure S3: Detailed results of the GO-term enrichment analysis for SKBR3 cells using the DAVID Bioinformatics resource. Figure S4: Enrichment map illustrating gene member overlap in the enriched GO-terms for SKBR3 cells treated with palmitate. Figure S5: Gene set enrichment analysis of significantly altered transcripts in SKBR3 cells after palmitate treatment. Figure S6: Exogenous palmitate does not alter the proteasome activity in HER2/neu-positive SKBR3 breast cancer cells. Figure S7: Expression of ER stress markers in HER2/neu-positive breast cancer cells upon treatment with palmitate. Figure S8: Alterations of ER stress regulators associate with alterations of regulators of the lipogenic phenotype previously described in HER2/neu-positive breast cancer cell lines. Figure S9: Her2/neu expression by itself has relatively minor effects on ER stress. Table S1: Primers used in expression analysis of ER stress markers. (DOCX 2241 kb) %I figshare