MOESM4 of Enabling low cost biopharmaceuticals: high level interferon alpha-2b production in Trichoderma reesei Christopher Landowski Eero Mustalahti Ramon Wahl Laurence Croute Dhinakaran Sivasiddarthan Ann Westerholm-Parvinen Benjamin Sommer Christian Ostermeier Bernhard Helk Juhani Saarinen Markku Saloheimo 10.6084/m9.figshare.c.3627284_D6.v1 https://springernature.figshare.com/articles/figure/MOESM4_of_Enabling_low_cost_biopharmaceuticals_high_level_interferon_alpha-2b_production_in_Trichoderma_reesei/4412759 Additional file 4: Figure S3. Protease activity measurements of purified fractions from culture supernatant sampled on day 4 and 5. The fractions from the pepstatin columns were measured at pH 4.5 and the SBTI fractions at pH 5.5. The protease activity on day 5 was higher than on day 4. 2016-06-10 05:00:00 Trichoderma reesei Filamentous fungi Interferon Therapeutic proteins Proteases Cytokines