10.6084/m9.figshare.c.3626939_D16.v1
Andrew Keniry
Andrew
Keniry
Linden Gearing
Linden
Gearing
Natasha Jansz
Natasha
Jansz
Joy Liu
Joy
Liu
Aliaksei Holik
Aliaksei
Holik
Peter Hickey
Peter
Hickey
Sarah Kinkel
Sarah
Kinkel
Darcy Moore
Darcy
Moore
Kelsey Breslin
Kelsey
Breslin
Kelan Chen
Kelan
Chen
Ruijie Liu
Ruijie
Liu
Catherine Phillips
Catherine
Phillips
Miha Pakusch
Miha
Pakusch
Christine Biben
Christine
Biben
Julie Sheridan
Julie
Sheridan
Benjamin Kile
Benjamin
Kile
Catherine Carmichael
Catherine
Carmichael
Matthew Ritchie
Matthew
Ritchie
Douglas Hilton
Douglas
Hilton
Marnie Blewitt
Marnie
Blewitt
MOESM10 of Setdb1-mediated H3K9 methylation is enriched on the inactive X and plays a role in its epigenetic silencing
Springer Nature
2016
H3K9 methylation
X inactivation
Epigenetic silencing
Setdb1
2016-05-18 05:00:00
Figure
https://springernature.figshare.com/articles/figure/MOESM10_of_Setdb1-mediated_H3K9_methylation_is_enriched_on_the_inactive_X_and_plays_a_role_in_its_epigenetic_silencing/4411847
Additional file 10. DNA methylation is largely unaltered upon Setdb1 depletion outside of X-linked CpG islandseRRBS data from Setdb1 +/+ Xist ∆A/+ 129/CAST transduced with Nons (Female) or Setdb1 +/gt Xist ∆A/+ 129/CAST transduced with shSetdb1.6 (Setdb1 depleted) MEFs, showing mC for individual CpGs on the Xa and Xi in Female (n = 3) and Setdb1 depleted female samples (n = 2), for CpGs outside CGIs on the X chromosome (Student’s two-tailed t-test) as log2(mC/C) (a), within CGIs on autosomes (b), outside CGIs on autosomes (c) and within CGIs with greater than 20% mC on autosomes (d). Note that autosomal data used is not allele specific. Dotted line indicates median for Xi in Female.