Additional file 1: Figure S1. of All-trans retinoic acid synergizes with topotecan to suppress AML cells via promoting RARα-mediated DNA damage XuZhifei ShaoJinJin LiLin PengXueming ChenMin LiGuanqun YanHao YangBo LuoPeihua HeQiaojun 2016 The TPT effect compared with doxorubicin (ADR). TPT induced cytotoxicity was Compared with ADR in AML cells. 4 × 103 cells per well were cultured in 96-well plates and incubated with the indicated concentrations of TPT and ADR for 48 h. Mean ± SD from three independent experiments. (TIF 10371 kb)