Additional file 2: of Inhibition of bromodomain and extra-terminal (BET) proteins increases NKG2D ligand MICA expression and sensitivity to NK cell-mediated cytotoxicity in multiple myeloma cells: role of cMYC-IRF4-miR-125b interplay
Maria Pia Abruzzese
Maria Bilotta
Cinzia Fionda
Alessandra Zingoni
Alessandra Soriani
Elisabetta Vulpis
Cristiana Borrelli
Beatrice Zitti
Maria Petrucci
Maria Ricciardi
Rosa Molfetta
Rossella Paolini
Angela Santoni
Marco Cippitelli
10.6084/m9.figshare.c.3624770_D10.v1
https://springernature.figshare.com/articles/figure/Additional_file_2_of_Inhibition_of_bromodomain_and_extra-terminal_BET_proteins_increases_NKG2D_ligand_MICA_expression_and_sensitivity_to_NK_cell-mediated_cytotoxicity_in_multiple_myeloma_cells_role_of_cMYC-IRF4-miR-125b_interplay/4405400
ULBPs and Nec-2 ligand expression on SKO-007(J3) cells following treatment with JQ1. ULBPs and Nec-2 surface expression were analyzed by immunofluorescence and flow cytometry on SKO-007(J3) cells treated with JQ1 as described above for 72Â h. The grey-colored histograms represent basal expression of the indicated ligand, while thick black histograms represent the expression after treatment with the drug. Data are representative of three independent experiments. (TIF 3116Â kb)
2016-12-01 05:00:00
Multiple myeloma
Bromodomain
IRF4
Natural killer
NKG2DLs