MOESM3 of Leptin decreases the expression of low-density lipoprotein receptor via PCSK9 pathway: linking dyslipidemia with obesity DuYing LiSha CuiChuan-Jue ZhangYan YangSheng-Hua LiJian-Jun 2016 Additional file 3: Figure S3. Knockdown efficiency of GAPDH siRNA in HepG2 cells. Real time PCR analysis of GAPDH mRNA levels in HepG2 cells transfected with GAPDH siRNA for 24 h. *p < 0.05 represent significant differences compared to the vehicle-treated cells.