10.6084/m9.figshare.c.3613871_D15.v1
Daniel Cook
Daniel
Cook
Babatunde Ogunnaike
Babatunde
Ogunnaike
Rajanikanth Vadigepalli
Rajanikanth
Vadigepalli
Additional file 12: Figure S11. of Systems analysis of non-parenchymal cell modulation of liver repair across multiple regeneration modes
Springer Nature
2015
Liver regeneration
Molecular regulatory mechanisms
Systems biology
Regeneration modes
Chronic liver disease
2015-10-22 05:00:00
Figure
https://springernature.figshare.com/articles/figure/Additional_file_12_Figure_S11_of_Systems_analysis_of_non-parenchymal_cell_modulation_of_liver_repair_across_multiple_regeneration_modes/4371965
Heatmap comparison of overall liver mass recovered for altered GF production and degradation rates. (A) Heatmap with rescaled color mapping showing a subtle effect of coarse-grained control of regeneration by GF production and fine-tuned control by GF degradation (legend below), (B) Mass recovery holding one parameter constant at 20 and varying the other, and (C) Mass recovery holding one parameter constant at 20 and varying the other between 0â20. All parameter changes are displayed in Fold change [FC] over nominal parameter value. The black line indicates when GF production rate fold change equals GF degradation rate fold change. Asymmetry around this line, as in (A), indicates a differential effect of GF production and degradation. (TIFF 235Â kb)